![]() ![]() In about 10 percent of cases, narcolepsy runs in families. genetically predisposed to the development of narcolepsy with cataplexy. I most strongly suspect a car accident and untreated whiplash, going with. However, the brain injury following whiplash injury has so far not been clearly. Episodes typically last a couple of minutes and resolve on their own. ![]() ![]() Unlike other conditions that cause a loss of muscle control, like fainting or seizures, people experiencing cataplexy remain conscious and aware. Less often, the cause of narcolepsy is an injury that damages the brain. I might have had narcoleptic seizures before this, passed off as nodding off. During more severe episodes, a person collapses and cannot move or speak. PMID: 23560595 DOI: 10.1111/jsr.12047 Abstract In a retrospective cohort study undertaken in 12 European countries, 249 female narcoleptic patients with cataplexy (n 216) and without cataplexy (n 33) completed a self-administrated questionnaire regarding pregnancy and childbirth. Their immune system mistakenly turns against their body and attacks the brain cells that produce hypocretin. Some people experience hallucinations and sleep paralysis when they’re falling asleep or waking up.Ĭertain people with autoimmune disorders are more likely to get narcolepsy with cataplexy. The lack of hypocretin makes it hard for someone to stay awake during the day, blurring the line between wakefulness and sleep. That loss of muscle tone causes you to lose control over your body when you’re awake. It’s the same loss of muscle tone that naturally happens during rapid eye movement (REM) sleep. Dual orexin antagonists induce physiological sleep by blocking orexin receptors. The loss of muscle tone, cataplexy, happens because sleep and wakefulness overlap in narcolepsy. PMID: 35022128 PMCID: PMC9059587 (available on ) DOI: 10.5664/jcsm.9882 Abstract Lemborexant is a dual orexin antagonist and is considered a safe and effective hypnotic. When it’s in short supply, your brain has trouble regulating your sleep-wake cycles. This chemical, which is produced in a brain region called the hypothalamus, controls sleep and wakefulness. Low levels of the chemical hypocretin cause narcolepsy with cataplexy. Narcolepsy affects signals in your brain that are supposed to keep you awake. ![]()
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